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Treatment

Vivitrol in West Virginia: How It Works and Who It Helps

Vivitrol is a monthly injection that treats opioid and alcohol addiction. Here's how it works, who it's for, and what to expect.

Published June 29, 2026

Vivitrol is a medication-assisted treatment option for opioid and alcohol addiction. It’s different from Suboxone because it’s not an opioid — it’s an opioid blocker.

This guide explains how Vivitrol works, who it’s for, and what to expect.

What is Vivitrol?

Vivitrol is the brand name for extended-release naltrexone. It’s given as a monthly injection in your buttock muscle.

What it does: Blocks opioid receptors in your brain. If you use opioids while on Vivitrol, you won’t feel anything. No high, no relief. This removes the reward, which helps break the cycle of use.

Vivitrol also reduces alcohol cravings and blocks the pleasurable effects of drinking.

How is Vivitrol different from Suboxone?

Suboxone is a partial opioid. It reduces cravings by gently activating opioid receptors.

Vivitrol is an opioid blocker. It completely blocks opioid receptors.

Key difference: You can start Suboxone while you’re still using opioids. With Vivitrol, you have to be fully detoxed first — 7-10 days off short-acting opioids, 10-14 days off long-acting opioids like methadone.

Who Vivitrol is for

Vivitrol works best for people who:

  • Have already detoxed and want to prevent relapse
  • Don’t want to take a daily medication
  • Prefer a non-opioid treatment
  • Have tried Suboxone and it didn’t work
  • Are motivated to stay in recovery

Vivitrol is NOT for:

  • People who are still actively using (you’ll go into withdrawal)
  • People who haven’t detoxed yet
  • People who need pain medication (Vivitrol blocks pain meds too)

How to start Vivitrol

Step 1: Detox

You have to be completely off opioids before you can get your first Vivitrol shot. This usually means:

  • 7-10 days off heroin, fentanyl, or prescription opioids
  • 10-14 days off methadone
  • 7 days off Suboxone

Your doctor will do a naloxone challenge test to make sure you’re fully detoxed. If you’re not, the Vivitrol shot will cause precipitated withdrawal.

Step 2: First injection

Once you’re detoxed, you’ll get your first Vivitrol injection. It’s given in your buttock muscle by a healthcare provider.

The injection site might be sore for a few days. That’s normal.

Step 3: Monthly injections

You’ll come back every 28 days for your next shot. You can’t skip doses — if you miss a shot, you lose protection and could relapse.

What Vivitrol feels like

Vivitrol doesn’t make you feel high or sedated. Most people don’t feel anything at all.

What it does:

  • Reduces cravings (for some people)
  • Blocks the effects of opioids if you use
  • Blocks the pleasurable effects of alcohol

What it doesn’t do:

  • Get you high
  • Make you drowsy
  • Impair your ability to work or drive

What if you use while on Vivitrol?

If you use opioids while on Vivitrol, you won’t feel anything. The Vivitrol blocks the opioid from attaching to receptors in your brain.

This can be frustrating, but it’s the point. It removes the reward.

Danger: Some people try to override Vivitrol by using large amounts of opioids. This is extremely dangerous and can cause overdose.

Does Vivitrol block pain medication?

Yes. If you need surgery or have a medical emergency, Vivitrol will block pain medication.

Important: Always tell doctors and dentists that you’re on Vivitrol. They’ll need to use non-opioid pain management options.

Side effects

Most people tolerate Vivitrol well. Common side effects:

  • Injection site pain or swelling
  • Nausea
  • Headache
  • Fatigue
  • Muscle aches

Serious side effects are rare but include:

  • Liver damage (your doctor will monitor this)
  • Severe injection site reactions
  • Depression

Vivitrol for alcohol use disorder

Vivitrol also treats alcohol addiction. It reduces cravings and blocks the pleasurable effects of drinking.

You don’t have to be detoxed from alcohol to start Vivitrol (unlike with opioids). But you do need to be committed to not drinking.

How long do you stay on Vivitrol?

There’s no set timeline. Some people stay on Vivitrol for 6 months. Some stay on it for a year or longer.

The goal is to give you time to build recovery skills, address underlying issues, and create a life where you don’t need opioids.

When you and your doctor decide you’re ready, you can stop. There’s no withdrawal from Vivitrol because it’s not an opioid.

Vivitrol vs Suboxone: Which is better?

Neither is better. They’re different tools for different situations.

Vivitrol might be better if:

  • You’ve already detoxed
  • You don’t want to take a daily medication
  • You want a non-opioid option
  • You’re highly motivated

Suboxone might be better if:

  • You’re still using and need help stabilizing
  • You can’t complete a detox safely
  • You need something that reduces cravings more strongly
  • You want more flexibility (can start while using)

What about counseling?

Vivitrol is not a standalone treatment. Counseling is required.

Medication blocks the physical cravings and effects, but it doesn’t address why you were using in the first place. Counseling helps you:

  • Understand triggers
  • Learn coping skills
  • Address trauma or mental health issues
  • Build a support system
  • Plan for long-term recovery

Cost

If you have Medicaid: Vivitrol is covered with little to no copay.

If you have private insurance: Most plans cover Vivitrol, but you might have a copay.

If you don’t have insurance: The manufacturer offers a patient assistance program. Community mental health centers can help you apply.

What if you relapse while on Vivitrol?

If you relapse, don’t stop your Vivitrol injections. Keep coming back for your monthly shot.

Relapse is part of recovery for a lot of people. It doesn’t mean Vivitrol failed. It means you need more support.

Talk to your counselor about what triggered the relapse and how to adjust your treatment plan.

The detox barrier

The biggest challenge with Vivitrol is getting through detox first. A lot of people can’t complete a 7-10 day detox on their own.

Options:

  • Medically supervised detox
  • Residential treatment program
  • Detox with comfort medications (not opioids)

If you can’t detox safely, Suboxone might be a better starting point. You can always switch to Vivitrol later.

Frequently Asked Questions

Can you drink alcohol while on Vivitrol?

Vivitrol reduces the pleasurable effects of alcohol, but it doesn’t make you sick if you drink. However, drinking while in recovery isn’t recommended.

Will Vivitrol show up on a drug test?

No. Vivitrol is naltrexone, which isn’t tested for on standard drug screens.

What happens if you miss a shot?

You lose protection. If you miss your monthly injection, you could relapse. Call your provider right away to reschedule.

Can you get the Vivitrol shot if you’re pregnant?

Talk to your doctor. Vivitrol hasn’t been extensively studied in pregnancy. Suboxone is usually preferred during pregnancy.

Does Vivitrol cause weight gain?

No. Vivitrol doesn’t typically cause weight changes.


If you’re interested in Vivitrol treatment in Southern West Virginia, you can call Southern Highlands’ Vivitrol program at (304) 425-9541 ext. 1525. They serve Mercer, McDowell, and Wyoming counties.

Important Numbers and Websites

24/7 Crisis Line

1-800-615-0122

Available 24 hours a day, 7 days a week

Crisis Stabilization Unit (CSU)

(304) 431-2869

Direct line for crisis assessment

Mobile Crisis (Adult & Adolescent)

(304) 308-9293

988 Suicide/Crisis Lifeline

988

Crisis Text Line: Text HOME to 741741

988lifeline.org / crisistextline.org

National Sexual Assault Hotline

(800) 656-4673/HOPE rainn.org

National Runaway Safeline

(800) 786-2929/RUNAWAY 1800runaway.org

WV Safe Schools Helpline

(866) 723-3982/SAFEWV wvde.us

SAMHSA National Helpline

(800) 662-4357/HELP samhsa.gov

DHHR Centralized Intake for Abuse/Neglect

(800) 352-6513 dhhr.wv.gov

WV State Police

(304) 746-2100 wvsp.gov